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In this study, we found both PKA inhibitors (Rp-cAMP and H-89) and PI3K inhibitors (LY294002 and wortmannin) abrogated the anti-apoptotic effect of GLP-1 in RINm5F cells based on the results of MTT assay (Fig

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Week 3, right arm

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With that being said, over one-third of participants in the trials did not progress to the highest dose, possibly because they could not tolerate the medication