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Some customers reported serious illness after injections, and authorities in multiple states are investigating related complaints

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In addition, the brain regions involved in mediating the effects of GLP-1 on gastric emptying and satiety differ, given that the threshold dose of GLP-1 required to inhibit gastric emptying is 3,000 to 10,000 times lower than the reported threshold doses necessary to suppress feeding behavior (161)

The results showed that retatrutide significantly delayed gastric emptying, reduced food intake, and caused dose-dependent WL