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Side effects tied to peak concentration (nausea, vomiting) might be slightly reduced with split dosing, which is why some patients on compounded tirzepatide do split their weekly dose into two mid-week injections during titration

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Readers interested in this outcome area may also want to review our guides on peptides for skin research and what GHK-Cu is, a copper peptide studied for many of the same connective-tissue pathways available as GHK-Cu

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