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This dual mechanism produces greater effects: clinical trials show tirzepatide produces approximately 2.0-2.3 percentage point reductions in HbA1c (versus 1.5-1.8 for semaglutide) and 15-22% weight loss (versus 10-15% for semaglutide)

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In addition, subcutaneous injection offers a variety of benefits including self-medication and shorter administration time, facilitating better adhesion to the treatment and lowering overall costs

Note that 100mg vials at daily 2mg dosing provide 50 days of product, which exceeds the 30-day reconstituted stability recommendation