GLP-1s support weight loss by: Delaying gastric emptying, which helps you feel fuller for longer after meals Regulating blood sugar, which can support steady energy and fewer cravings Reducing appetite and food noise by acting on hunger-regulating areas of the brain While Ozempic, Wegovy, Foundayo, and Zepbound all fall under the GLP-1 umbrella, Zepbound is unique in that it also targets another hormone called GIP (glucose-dependent insulinotropic polypeptide)
Some retrospective analyses suggest patients using GLP-1 medications may experience fewer RA flares or reduced inflammatory markers compared to those on other diabetes treatments
While some individuals may begin to notice a reduction in hunger within the first week of starting treatment, the full effects typically develop over a period of several weeks
Looking forward, longer term studies will be necessary
Parker CH, Slattery C, Brennan DJ, le Roux CW