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A body composition substudy of the Phase 2 diabetes trial, published in The Lancet Diabetes & Endocrinology in 2025, used DXA scans to measure changes in fat and lean mass in 189 participants
Its not unusual for patients to stop taking GLP-1 drugs in the real world beyond these clinical trials, notes Marilyn Tan, MD, a professor at Stanford University School of Medicine and chief of the endocrine clinic at Stanford Health Care in California
Depending on how Lily defines LRE, this approach may not be smaller or cheaper, but is for sure far more clinically relevant than biopsy outcomes
Mechanism in research literature Triple-receptor agonism is the central pharmacological feature of the molecule
2016;14(1):12431 e1
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