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Murine primary chondrocytes or RAW 264.7 cells were stimulated with 2 ng/mL of IL-1 or 100 ng/mL of lipopolysaccharide (LPS), respectively, and co-treated with ascending concentrations of liraglutide (6.6, 13.3, 26.6, 53.1, 106.3, 212.5, 425, 850 nM, 1.7 and 3.4 M) at 37C + 5% CO 2 for 24 h

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Consideraciones para reduccin gradual: En pacientes que alcanzan remisin de diabetes tipo 2 mediante prdida ponderal significativa y cambios de estilo de vida sostenidos, puede considerarse reduccin gradual bajo monitorizacin estrecha

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