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The effect of a GLP-1 receptor agonist, liraglutide, on -cell glucose sensitivity was examined in a placebo-controlled crossover study involving 10 patients with well-controlled type 2 diabetes (mean hemoglobin A1c [HbA1c], 6.5%) and 10 healthy subjects [8]
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TRAP staining revealed a similar number of osteoclasts in MSC- Igf1r / mice compared to their wildtype littermates (Figure 5, bottom panel), further indicating that the decreased bone volume observed by CT was due to decreased bone formation rather than enhanced bone resorption
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