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Nonetheless, the deletion of Nrf2 prevented the increased expression of NRF2 protein and the induction of NRF2 targets upon Gclc deletion in liver tissue (Fig
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The lack of statistically significant effect on this outcome, which was repeatedly demonstrated to improve in the CVOTs with GLP-1 RAs [12], can be explained by the irregularity of UACR sampling in real-world setting compared with CVOTs