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We carefully control temperature and time to maintain the stability of the vesicles

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Cardiovasc Res 61:402413 Shah U, Joshi G, Sawant KJMS (2014) Improvement in antihypertensive and antianginal effects of felodipine by enhanced absorption from PLGA nanoparticles optimized by factorial design

In addition, complementing advanced MRI and molecular imaging with minimally invasive fluid biomarkers may improve discrimination between true tumor progression and treatment-related changes, while also providing earlier readout of tumor-associated neuroaxonal and glial injury ( Figure 2B )