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doi: 10.1016/j.phrs.2020.105243 90 HeFRuXWenT

Although all authors agree for the presence of GLP1R in the pancreatic islets, there are differences at the level of ducts: whereas Krner et al , 2 Pyke et al , 24 and Drucker, 11 using GLP1R autoradiography, immunohistochemistry, or mRNA analysis, respectively, were unable to detect GLP1R in human ducts, Gier et al 25 found such receptors in rat and human pancreatic ducts by immunohistochemistry

This can be considered a limitation and should be addressed in future studies

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P 135/85 mmHg during awake period and 120/70 mmHg during sleeping period) were significantly increased after liraglutide compared to placebo in patients with eGFR 60 ml/min/1.73 m 2 (Table 3)