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Two types of well stations are being built wells housed inside buildings with separate rooms for the well and chemical treatment and wells housed in outdoor, fenced enclosures without chemical treatment

9 In addition, secretion is regulated by thyroid hormones, leptin, androgens, and estrogen

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The multiple pharmacological treatment options will enhance clinicians ability to identify effective personalised regimens by trying a second medication or combining medications with synergistic or complimentary actions or even escalating treatment to bariatric surgery based on patient preference and underlying comorbidities [7]