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For retatrutide , phase 2 data published in the New England Journal of Medicine (2023) demonstrated substantial mean weight reductions over 48 weeks in adults with obesity among the highest figures reported for any pharmacological agent to date

Congestive heart failure (CHF): NAD+ infusions may contribute to fluid overload or cardiac strain in patients with compromised heart function

Type 2 diabetes, cardiovascular disease, hypertension, fatty liver disease, and obstructive sleep apnea all represent serious health risks that GLP-1 medications help address