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Hydrogels have been designed and synthesized loaded with a miR-223-5p mimic, which promotes the polarization of macrophages to M2-type macrophages in wound tissue and upregulates the expression of the anti-inflammatory gene Arg-1 and downregulates the expression of TNF, IL-1, and IL-6 (Saleh et al., 2019)

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Selected Research References: Gwyer D et al., Cell and Tissue Research (2019) Examination of BPC-157 in musculoskeletal soft tissue research models

Values of PP were 4.7%, 1.6%, 3.3%, 5.1%, and 6.8% higher with the 1.5 g/d dosage compared with baseline values