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Advances in rheumatology: new targeted therapeutics
Following this strategy, different metabolic pathways for carbohydrate, lipid, and protein metabolism could be influenced simultaneously
Evolution of sodium-glucose co-transporter 2 inhibitors from a glucose-lowering drug to a pivotal therapeutic agent for cardio-renal-metabolic syndrome
TMAO exerts pro-atherogenic and pro-inflammatory effects that contribute mechanistically to several chronic inflammatory diseases including cardiovascular disease, chronic kidney disease, obesity, non-alcoholic fatty liver disease, and neurodegenerative diseases
Shorter cycles will see proportionally smaller weight-change endpoints than the full trial-length numbers
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