Its defining structural feature is the gamma-glutamyl linkage: the glutamate residue is joined through its side-chain carboxyl rather than the usual alpha-peptide bond, which makes the molecule resistant to most intracellular peptidases and means it is cleaved almost exclusively by gamma-glutamyl transpeptidase at the outer cell surface (Zhang, Forman and Choi, Methods in Enzymology, 2005)
(2012) Miscellaneous pathogens In, Bacterial Fish Pathogens: Disease of Farmed and Wild Fish Springer Science+Business Media Dordrecht, pp 413-441 19
Since then, the peptide has been the subject of hundreds of scientific publications examining its properties at the molecular and cellular level
Our controlled batch production process includes multiple stages of purification and verification to ensure the integrity of each component and the final blend
Distinct roles for LFA1 affinity regulation during T-cell adhesion, diapedesis, and interstitial migration in lymph nodes
