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The most important clinical outcome of CHE is its progression to OHE with an annual incidence rate of 10% [20]

Studies on mice models showed that a high-fat diet correlates with decreased GLP-1 production, reduced GLP-1 receptor sensitivity, impaired ghrelin secretion, and sensitivity, thus determining a diet-induced low-grade organ-specific and systemic inflammation [28]

Q4: What is the suggested dose for adult cattle