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This is because intravenous administration bypasses the digestive system, allowing for quicker absorption at higher concentrations

The Enteric Nervous System and Its Emerging Role as a Therapeutic Target

Oxford: Oxford University Press

We are encouraged to see that delivery of semaglutide via the RaniPill capsule demonstrated comparable bioavailability, pharmacokinetics and weight loss to subcutaneous administration of semaglutide at the same dose, said Talat Imran, Chief Executive Officer of Rani Therapeutics

This information is based on clinical studies and prescribing information provided by the manufacturer