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MT-1s MC1R-preferential activity makes it the primary research tool for studying MC1R biology in pigmentation, photoprotection, and skin immunology without the confounding central melanocortin receptor activation that limits the interpretability of studies using less selective melanocortin agonists

Kamat, N

Keeping a symptom journal during tirzepatide treatment helps distinguish between medication effects, coincidental illness, and indirect consequences of the metabolic changes the drug produces

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