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Proactive hydration practices prevent this cascade entirely

Concurrently, TNF- and TGF-1 drive CSMC apoptosis and fibroblast-like phenotypic transformation, resulting in cavernous fibrosis and reduced tissue distensibility, while inflammatory cytokines and excessive ROS impair penile nerve integrity and neurotransmitter release, exacerbating neurogenic ED in animal studies (205)

Because your body uses them every day to manage oxidative stress, consistent use is required to see a meaningful difference