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Restoring Lower Esophageal Sphincter Function Sphincter dysfunction sits at the core of GERD pathophysiology

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Significant improvements in hemoglobin A1c typically become apparent after 12 weeks, while weight loss continues progressively over 612 months

The Weight Management segment represents approximately 31.2% of market revenue in 2025 but is growing significantly faster at a projected CAGR of 19.4% versus 14.8% for Diabetes Treatment, driven by Wegovy's expanding global approvals and the SELECT trial's cardiovascular label update