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Do not escalate based on calendar alone

The FDA approved semaglutide in 2017

Each pen has four doses, one for each week, which is about a one-month supply

Among the 32 compounds that most strongly reduced bioluminescence, 31 did not alter persister frequencies, indicating that they probably suppressed bacterial metabolism rather than killing persisters (Supplementary Fig

We are also interested in the correlated changes across all three modalities, as the comparison between brain metabolism and function has important implications for medical imaging biomarkers, both when metabolism and function are correlated [27] and also when they diverge [28]