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FDA-approved for three indications with multiple active-comparator trials, cardiovascular outcomes data, and extensive post-marketing surveillance

Possible role of PEPT1 in gastrointestinal hormone secretion

PubMed Carbo M, Segura J, De la Torre R, et al

Interestingly, in people with type 2 diabetes mellitus, who often exhibit glomerular hyperfiltration, GLP-1 receptor agonists stabilize or modestly reduce eGFR, an effect reminiscent of the initial declines observed with RAAS and SGLT2 inhibitors [64]

We have therefore included a table of all our statistical analyses with effect sizes as a reference for power analyses for future studies