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Both medications activate GLP-1 receptors, yet they differ in mechanismtirzepatide is a dual GLP-1/GIP receptor agonist, while semaglutide targets GLP-1 alonemaking the switch distinct from simple dose adjustment

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Pairing it with anti-inflammatory peptides like BPC-157 may help mitigate side effects by supporting sustained follicle health without hormonal interference

Our findings demonstrate significant reductions in mortality, MAKE, and MALO across diverse patient populations, suggesting that this therapeutic approach could represent a paradigm shift in MASLD management