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The first cannabanoid-1 receptor antagonist to enter clinical trials was rimonabant, which showed excellent weight loss outcomes with an additional mean weight loss of 4.7 kg [102]

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As Dani Blum noted in a recent New York Times article, a growing amount of medical research suggests that if youre taking GLP-1 drugs now, youre going to be in it for the long haul lest you risk regaining some or all of the weight that you lost along the way