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Gently swirl the vial to dissolve the compound

Ligand binding triggers receptor autophosphorylation and recruitment of insulin receptor substrate (IRS-1, IRS-2) and Shc adapter proteins, activating the PI3KAktmTOR and RasRafMEKERK signaling cascades

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When PT-141 activates MC4R, it triggers the cascade of neural and hormonal responses involved in sexual response