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Week 1: Dose: 50mcg Frequency: Once, on a night when you can sleep in the next morning Timing: 2-3 hours before intended sleep Purpose: Assess basic tolerance and response Week 2: Dose: 75-100mcg Frequency: 2-3 times during the week Timing: 1-2 hours before bed Purpose: Establish baseline effective dose During this assessment phase, track sleep quality subjectively and, if possible, with a wearable device that measures sleep stages

Was the research conducted in human participants

An upright position allows gravity to assist with gastric emptying, which reduces the bloated, overly full feeling that triggers nausea

Supplementing with B12 may lead to improved mood and a reduced risk of mood disorders