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PPAR can slow cartilage degeneration and bone destruction by downregulating matrix metalloproteinases (MMP-3, MMP-13) 51

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Research in various animal models demonstrates TB-500 improves muscle fiber regeneration, including in chronic degenerative conditions

SARS-CoV-2 and its massive cytokine storm primarily compromises the lungs causing acute respiratory distress syndrome also affecting the cardiovascular system aggravating atherosclerotic lesions leading to thromboembolic events and cell and tissue death (Ryu and Shin, 2021

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