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The typical regimen involves: Loading dose for patients without neurological involvement : Hydroxocobalamin 1mg intramuscularly three times weekly for two weeks [13] [10] Loading dose for patients with neurological involvement : Hydroxocobalamin 1mg on alternate days until no further improvement, then Maintenance therapy : 1mg every two to three months (or every two months if neurological involvement) Lifelong maintenance therapy is necessary for irreversible causes such as pernicious anaemia or following gastric surgery
Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men: A RCT
Sideek et al., 2024)
The article is candid that the combination has not been extensively studied as a single product
Horsch D, Goke R, Eissele R, Michel B, and Goke B
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