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Polyphenols such as resveratrol, fisetin, quercetin and curcumin have been shown to modulate SIRT1 signalling in cells, animals and a limited number of humans, resulting in improvements to markers of oxidative stress, metabolism and neuroprotection [117,118,119,120]

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doi: 10.7554/eLife.19375 75 MeniniSIacobiniCde LatouliereLManniIVitaleMPilozziEet al