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Avoiding past failures The past landscape of weight loss drugs is littered with failures, however
This association between liver disease and DPP-4 has been confirmed in other studies, showing higher plasma levels (85, 86) as well as higher hepatic Dpp4 expression (87) in the patients compared to healthy individuals
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Others find success by optimizing diet composition: shifting to higher protein intake (which amplifies GLP-1 satiety), reducing processed carbohydrates, and maintaining consistent meal timing can synergize with medication effects
Coffee, in particular, can be both a trigger for reflux and a hidden source of calories when prepared with cream or syrup
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