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Specifically, eligible studies included participants (P) with a confirmed diagnosis of vitamin B12 deficiency, interventions (I) involving oral or sublingual vitamin B12 administration, comparators (C) using intramuscular supplementation, and outcomes (O) reporting changes in serum vitamin B12 or homocysteine levels

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It also activates proteins known as sirtuins that regulate DNA repair and cellular longevity

Vitamin B12 injection dosage for adults: Benefits, frequency, and duration