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Ozempic also slows down the digestion of food and the rate that food leaves the stomach to head into the digestive tract

Maintaining normal conditions at the injection site keeps absorption predictable

However, central administration of LEAP2 reduces binge-like intake of a HFD, an effect not observed with central ghrelin administration or with pharmacological blockade of GHSR using the antagonists [D-Lys3]-GHRP-6 and JMV2959

doi:10.1007/s00125-017-4354-8 [6] Zimmermann T, Thomas L, Baader-Pagler T, et al

When side effects occur, they are usually mild to moderate gastrointestinal symptoms (nausea, constipation, indigestion) and tend to ease as your body adjusts