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Aetna's clinical policy bulletin (CPB 0784) now expects documented weight management attempts of at least 6 months before approving GLP-1 coverage on most plans (up from 3 months on some 2025 plans)

Conversely, mishandling can introduce degradation or impurities that may not always be visible, leading to flawed data or wasted material

doi: 10.1016/S0140-6736(69)92278-8 25 CooperMRDeChateletLRMcCallCELaViaMFSpurrCLBaehnerRL

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Your doctor should verify thyroid function before starting treatment and recheck labs 8 weeks into therapy