The work of Bock-Marquette and collaborators (2004) demonstrated the cardioprotective effect of thymosin beta-4 in a murine model of myocardial ischemia, a finding confirmed by several independent teams
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Addressing underlying health Issues: Sometimes, symptoms attributed to HPA axis dysregulation can be due to other underlying health issues, like thyroid disorders, iron-deficiency anemia, hidden infections, or depression, for example
Furthermore, anticholinergic medications, such as trihexyphenidyl, are used also in PD management but struggle to effectively cross the BBB and often exhibit non-specific binding, leading to undesirable peripheral effects such as dry mouth and cognitive impairment, particularly in elderly patients