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The safety profile of cagrilintide, as observed in clinical trials , is primarily characterized by gastrointestinal disturbances , most notably mild to moderate nausea during the initial titration phase

DSIP (Delta Sleep-Inducing Peptide) 7

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Considering an estimated average blood volume of approximately 7%8% of body weight in mice ( in vitro IC50 of 613 M for hepatocytes, taking into account the rapid distribution and metabolism occurring in vivo