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Within this framework, traditional concerns regarding ATP synthesis deficits (68, 69, 75), dysregulated post-exercise phosphocreatine (PCr) resynthesis kinetics (88, 89),metabolic stress via the AMPK pathway (7174), and the direct impact of ATP insufficiency on neuromuscular function can all be integrated as downstream events stemming from this central mechanism (7880)

10.3389/fimmu.2021.652782 110 WeiM.ZhengZ.ShiL.JinY.JiL

Grip strength and VO2 max emerge as top health biomarkers