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Researchers working with intranasal peptide formulations should consider the following variables: Mucosal enzymatic activity: The nasal epithelium contains proteolytic enzymes that may degrade peptides before absorption Molecular weight constraints: Smaller peptides may absorb more efficiently
doi: 10.1074/jbc.m117.791285 23 LiuLMiaoZ-WWeiY-ZBuSGuXXuYet al
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