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Moreover, CRSR was found to affect various ECM-associated genes, which may be responsible for its ability to decrease uterine mass (Yu et al., 2019)

No serious adverse events, clinically significant cardiovascular effects, or mutagenic, teratogenic, or fertility-related risks have been reported, supporting its favorable safety profile, including in pediatric populations (Verlaet et al., 2017)

When Ca2+ is triggered to release from intracellular stores there is a resulting positive inotropic effect without the possibility of eliciting a drastic change in heart rate

K.WatkinsC.GuptaA.BlackshawS.et al (1999)