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This is an important safety distinction

It's Designed to Penetrate, Not Just Sit on the Surface Serums use lower-molecular-weight actives suspended in a lighter base, which allows them to reach the dermis (the deeper layer of skin), where actual correction occurs

This explains why 2-3 weekly injections produce cumulative collagen synthesis and sustained anti-aging benefits despite rapid peptide elimination

It also plays a key role in recycling other antioxidants, such as Vitamin C and Vitamin E, keeping them in their active forms

Research demonstrates that BPC-157 upregulates VEGFR2 at both mRNA and protein levels in vascular endothelial cells without increasing VEGF-A itself, effectively sensitizing cells to existing VEGF in the tissue microenvironment rather than simply adding more growth factor signal