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Insecticidal, antimicrobial and antioxidant activities of bulb extracts of Allium sativum

These metabolites significantly contribute to the pathophysiology of ACM through multiple pathways: they modulate immune responses, alter cardiac metabolism, and interact with receptors in cardiac tissue (177)

Cannone V, Boerrigter G, Cataliotti A, et al

When acetyl-CoA accumulates in mitochondria, the enzyme converts the accumulated acetyl-CoA to acetyl carnitine, reduces the acetyl-CoA/CoA ratio in mitochondria, promotes the activity of pyruvate dehydrogenase complex, and promotes the oxidative decarboxylation of pyruvate to acetyl-CoA (Calvani et al., 2000)

Al unirse a los receptores de GLP-1 presentes en la superficie de estas clulas, los anlogos desencadenan una cascada de eventos moleculares altamente regulados