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[16] [17] Semaglutide (as Wegovy) is further indicated as an adjunct to a reduced-calorie diet and increased physical activity for weight management, including weight loss and weight maintenance, in adults with obesity (initial BMI 30 kg/m 2 ) or who are overweight (initial BMI 27 kg/m 2 ) and have at least one weight-related comorbidity such as dysglycemia (prediabetes or type 2 diabetes), hypertension, dyslipidemia, or cardiovascular disease

Energy expenditure rises

The key to preventing muscle loss on semaglutide and IF lies in a combination of strength training and adequate daily protein and energy intake

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The American Journal of Managed Care .