2 months on tirzepatide 14 lbs down in her first months. She had been eating well and trying to work out and wasn't seeing any progress. We added some and increased her protein goals Restarting Tirzepatide After a Month:

Staying on semaglutide for longer periods allows your brain and metabolism to adapt more deeply to lower calorie intake and increased satiety

Why does the post say a 22-year-old with a normal BMI would not qualify

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McCutcheon JE, Ebner SR, Loriaux AL, Roitman MF (2012)

and CPT1C is expressed in the brain ( CPT1A and CPT1C rather than CPT1B , and we speculate that this may have been because these two isoforms showed lower abundance in cardiomyocytes and were thereby more sensitive