1997;272(49):307806, PMID 9388218 (en) Patrick L
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The peptide enhances Wnt/-catenin signaling, a critical pathway for hair follicle development and regeneration, while simultaneously suppressing TGF- signaling in the follicle bulge region where stem cells reside
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The discovery has revealed that natural plant polysaccharides possess the ability to exert antidepressant effects through the regulation of neurotransmitters and their receptors, modulation of the HPA axis, control of inflammatory responses, management of oxidative stress, modulation of neurotrophic factors, regulation of gut microbiota and tryptophan metabolism, as well as other pathways