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The skin needs time to complete its collagen remodeling cycle

The nasal spray format enables intranasal delivery research

High-frequency data collection, such as daily diaries, offers greater insight into patient experience but also introduces additional variability

Adverse events [edit] In general, the safety profile of tesofensine is similar to currently approved medications for the treatment of obesity

Importantly, 70-80% of participants achieved at least 10% weight loss (the threshold for clinically meaningful benefits), and 50-60% achieved at least 20% weight loss (approaching surgical weight loss results without surgery)