Key experimental observations include: Preserved Bone Formation: Rodent models demonstrate maintained periosteal activity and longitudinal growth rates despite controlled dosing, indicating localized skeletal responsiveness without broad endocrine activation
Age-related decline (Caplans findings): At birth: ~1 in 10,000 marrow cells are MSCs Teen years: ~1 in 100,000 Age 50: ~1 in 400,000 Age 80: ~1 in 2,000,000 Why perinatal sources: Epigenetic youth Day-one signaling vigor supports robust paracrine orchestration Safety and ethics Not fetal tissue
It does this by actually measuring the DNA of the microbes in your GI tract
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