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doi: 10.1530/EJE-18-0175 66 ZelnikerTAWiviottSDRazIImKGoodrichELFurtadoRHM

Moreover, dual-targeted nanoparticle M2NPs formed by the addition of a peptide (scavenger receptor B-type 1 targeting peptide) to an M2 macrophage binding peptide (M2NP) and loading with anti-CSF-1R small interfering RNA (siRNA) can significantly eliminate M2-like TAMs by specifically blocking the survival signal of M2-like TAMs thereby shrinking tumors and prolonging survival (19)

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