The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions
An updated systematic review and network meta-analysis of GLP-1 receptor agonists and polyagonists ranked retatrutide at or near the top for weight loss among the modern agents, while also flagging that the strongest-effect agents tend to carry the highest adverse-event burden
Among these products, berberine, chromium, cinnamon, curcumin, and probiotics have the potential to improve glycemic control and, in some cases, to modulate GLP-1 signaling
Caltabiano et al., 2020)
4 Between GLP-1s ability to boost insulin and control glucagon for healthy blood sugar levels and to help slow digestion and help you feel full faster, the buzz around this hormone makes a lot of sense