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(2016) 41:S26682

Emphasize lifestyle interventions (nutrition, exercise) to sustain metabolic gains following drug cessation, minimizing rebound weight gain and reproductive fluctuations

Has been used successfully for treatment of erectile dysfunction

Similarly, environmental enrichment, which provides enhanced sensory, cognitive, and motor stimulation, can elevate BDNF levels and, when combined with therapies that bolster TrkB expression (as demonstrated with the peptide P42 in an HD mouse model), synergistically delays disease progression and improves motor and cognitive outcomes (Couly et al., 2021)

There is no trial in which CagriSema and tirzepatide were given to comparable participants and measured against each other