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Safety Considerations and Medical Monitoring Requirements Neither semaglutide nor steroids should be stopped abruptly, but combining them complicates the picture
When to seek medical advice: If you experience muscle pain, weakness, or dark urine whilst taking statins (potential signs of myopathy) If severe, persistent abdominal pain occurs whilst on GLP-1 therapy (potential pancreatitis) If cholesterol reduction is not achieved despite treatment adherence Before stopping or changing any prescribed medication If you develop new symptoms or side effects from any therapy Patients should discuss their individual cardiovascular risk profile and treatment options with their GP or specialist
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Factors That May Affect Your Starting Dose Starting dose and escalation speed are influenced by BMI, renal and hepatic function, gastrointestinal history, concomitant glucose-lowering medications, and age
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